Katherine Kay, Ph.D.

Research Scientist & Reporting Specialist I

Katherine joined Metrum in August 2018 as a Research Scientist. Katherine completed her Ph.D at Liverpool School of Tropical Medicine (LSTM), University of Liverpool, UK. Her dissertation work involved developing and implementing pharmacokinetic-pharmacodynamic (PK-PD) models of antimalarial drug action. In collaboration with the Swiss Tropical and Public Health Institute (Swiss TPH), Katherine translated these models of drug action into their open-source simulation platform of malaria epidemiology and control, “OpenMalaria”. Katherine continued to collaborate with Swiss TPH as a post-doctoral research associate based at LSTM. Her work extended antimalarial PK-PD model methodology to investigate drug resistance and to optimize dosing regimens in malaria treatment, and contributed to ongoing insecticide resistance modeling.

In 2015, Katherine moved to the University at Buffalo, NY, USA, where she developed a physiologically-based pharmacokinetic (PBPK) model to characterize the physiological structure of the vaginal space and the absorption/distribution of vaginally administered drugs. The model specifically focused on the administration of antiretroviral compounds delivered via either a ring or film formulation and aimed at optimizing the probability of success of vaginally administered antiretroviral drugs.

Recent publications by this scientist

Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp

September 14, 2019

Presentation by Katherine Kay Ph.D at R/Medicine. Boston, MA. 14 September 2019.


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Development of an open-source physiologically-based pharmacokinetic model to predict maternal-fetal exposures of CYP450-metabolized drugs

July 16, 2019

Gastonguay MS, Russell S, Freling R, Riggs M, Kay K, Utsey K, Elmokadem A.

Poster presented at 2019 American Society for Clinical Pharmacology & Therapeutics (ASCPT). Washington DC. 14 March 2019.

Poster presented at ISoP Regional QSP Day 2019. Princeton, NJ. 16 July 2019.

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