Ahmed Elmokadem, Ph.D.

Research Scientist I

Ahmed earned his PhD in Biomedical Sciences from the University of Connecticut. His thesis work revolved around building statistical models to solve problems with super-resolution imaging. Other fields of experience include systems biology and pharmacokinetics. More recently, he focused on developing physiologically-based pharmacokinetic (PBPK) models to get a better mechanistic understanding of drugs’ pharmacokinetics.

Recent publications by this scientist

A physiologically-based pharmacokinetic modeling approach to support candidate and first in human dose selection for bamlanivimab

September 3, 2021

Tim Knab, Ahmed Elmokadem, Emmanuel Chigutsa, Eric Jordie, Matthew Riggs, Patricia Brown-Augsburger, Christopher Wiethoff, Ajay Nirula, Jenny Y Chien, Lisa O’Brien.  Poster presented at Population Approach Group Europe Annual Meeting; 2-3 and 6-7 September 2021.  Poster I-64.

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Impact of Obesity on Brexpiprazole Pharmacokinetics: Proposal for Improved Initiation of Treatment

August 2, 2021

Bruno, C. D., Elmokadem, A., Housand, C., Jordie, E. B., Chow, C. R., Laughren, T. P., & Greenblatt, D. J. (2021). Journal of clinical pharmacology.  20211– 11https://doi.org/10.1002/jcph.1947

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Brexpiprazole Pharmacokinetics in CYP2D6 Poor Metabolizers: Using Physiologically Based Pharmacokinetic Modeling to Optimize Time to Effective Concentrations

July 30, 2021

Elmokadem A, Bruno CD, Housand C, Jordie EB, Chow CR, Lesko LJ, Greenblatt DJ.  J Exp Pharmacol20211– 10https://doi.org/10.1002/jcph.1946

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