William R. Gillespie, Ph.D.

Senior Science Advisor, Fellow I

For over 20 years Bill has been involved in the development and application of pharmacometric methodology for enhancing drug treatment, development and regulation. His current interests include the use of Bayesian modeling and simulation to optimize decision-making in clinical drug development and treatment. He plans to make Bayesian modeling and simulation methods more accessible via training programs and development of software tools.

Recent publications by this scientist

Application of Model-Based Meta-Analysis to Set Benchmarks for New Treatments of Systemic Lupus Erythematosus

November 14, 2022

Kosalaram Goteti, Ramon Garcia, William Gillespie, Jonathan French, Lena Klopp-Schulze, Ying Li, Cristina Vazquez Mateo, Sanjeev Roy, Oliver Guenther, Lisa Benincosa, Karthik Venkatakrishnan. Poster presented at 2022 American Conference on Pharmacometrics (ACoP13). 30 October – November 2 2022. Poster T-075

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Bayesian PBPK Modeling using R/Stan/Torsten and Julia/SciML/Turing.jl

October 28, 2022

Ahmed Elmokadem, Yi Zhang, Tim Knab, Eric Jordie, William R. Gillespie. Poster presented at 2022 American Conference on Pharmacometrics (ACoP13). 30 October – November 2 2022. Poster W-074

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Flexible and efficient Bayesian pharmacometrics modeling using Stan and Torsten, Part I

May 15, 2022

Charles C. Margossian, Yi Zhang, William R. Gillespie. Flexible and efficient Bayesian pharmacometrics modeling using Stan and Torsten, Part I. CPT Pharmacometrics Syst Pharmacol. 2022 May 15. doi: 10.1002/psp4.12812. Epub ahead of print. PMID: 35570331.

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