Dose-response and exposure-response modeling of alpha-1 proteinase inhibitor (A1-PI) in patients with A1-PI deficiency based on RAPID and RAPID extension trials

Rogers JA, Tortorici MA, Viti O, Brexon M, Sandhaus RA, Burdon J, Piitulainen E, Seersholm N, Stocks J, McElvaney NG, Chapman KR, Edelman JM.  Presented at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting, San Diego, CA, March 2016.