Many of our clients have benefitted immensely from using interactive apps to make decisions throughout the drug development process. These apps allow decision making teams to quickly and easily access the complexities of models and simulators. Deploying these apps within Metworx allows for the quick and reproducible analysis of various scenarios by both technical and nontechnical stakeholders.
Check out some examples of apps we have developed by clicking on the links below.
HBGDki M3 Gut & Growth Model
To understand and separate effects of nutrition and disease on infant growth, a physiologically-based mathematical model was developed describing fat mass (FM) and fat-free mass (FFM) from birth to 2 years. This app allows a user to simulate individual infant phenotypes and infection events and visualize growth and energy levels over time, relative to healthy (WHO) standards.
This app demonstrates simulation from a published quantitative systems pharmacology (QSP) model for ERK inhibition in colorectal cancer. It was used in our workshop “Toward Open Science: Translating literature-reported quantitative pharmacology models for simulation and interactive visual exploration”.