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October 2019

DIA Pediatric Drug Development Workshop

October 28, 2019 @ 7:00 am - October 29, 2019 @ 5:00 pm
Hyatt Regency Bethesda, 7400 Wisconsin Avenue
Bethesda, MD 20814 United States
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Join CEO Marc Gastonguay, Ph.D., who will be speaking at the DIA Pediatric Drug Development Workshop.

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November 2019

CTSI Disease and Therapeutic Response Modeling and Simulation Symposium

November 11, 2019 - November 12, 2019

This two-day program, the 9th annual hosted by Indiana University School of Medicine, will include speakers from academia, industry, and regulatory agencies. Hine Hall Indianapolis, IN November 11-12, 2019

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Development of Best Practices in Physiologically Based Pharmacokinetic Modeling to Support Clinical Pharmacology Regulatory Decision-Making

November 18, 2019 @ 8:00 am - 5:00 pm

Join CEO Marc Gastonguay, Ph.D., who will be a panelist for a session at the FDA Workshop: Development of Best Practices in Physiologically Based Pharmacokinetic Modeling to Support Clinical Pharmacology Regulatory Decision-Making.

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January 2020


January 27 - January 30
san fransisco, CA,

rstudio::conf, the conference for all things R and RStudio, will take place January 29 and 30, 2020 in San Francisco, California.

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March 2020

ASCPT – American Society for Clinical Pharmacology & Therapeutics

March 18 - March 21

The ASCPT Annual Meeting for 2020 will be held in Houston, TX. Meet MetrumRG scientists at the event!

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Bayesian Methods in Drug Development Decision Making: Challenges and Value Proposition

March 21 @ 2:00 pm - 5:00 pm
Marriott Marquis Houston, 1777 Walker Street
Houston, TX 77010 United States
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A free ASCPT post-conference workshop and reception sponsored by Metrum Research Group Date: Saturday, March 21, 2020 Time: Workshop - 2:00-4:00PM (CST), Reception - 4:00-5:00PM (CST) Instructors: Marc R. Gastonguay & Matthew M. Riggs Space is limited. No more than 4 attendees from a given institution or company, please. Workshop Overview Bayesian data analysis methods are well suited for decision making in drug development and therapeutics due to their formal inclusion of prior information and specification of inferences in terms…

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June 2020

A Gentle Introduction to Optimal Design for Pharmacometric Models

June 8 @ 12:00 pm - 1:00 pm

Throw open the basement hatch (virtually) and join Metrum Research Group for an open-learning approach to open-science.

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August 2020

StanCon 2020

August 13

Join MetrumRG scientists at StanCon 2020, which will be presented virtually. Information and registration can be found here: https://mc-stan.org/events/stancon2020/

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September 2020

Analysis & Reporting of QTc Prolongation Potential of New Drugs Using R Tools, Expectations & General Guidance for Regulatory Submissions

September 19 @ 8:00 am - 11:30 am

Ana Ruiz-Garcia, PharmD, PhD, joins Dhananjay D. Marathe, PhD, to co-chair a pre-meeting workshop for the virtual American College of Clinical Pharmacology's annual meeting. Attendees of the workshop will be able to become familiar with the ECG-pharmacokinetic analysis using R, create a report using R Markdown, Gan understanding about the sample size and exposure margin requirements for TQT substitution request based on studies without a positive control and bring a deeper understanding of some of the common challenges and potential…

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October 2020

A PK & PBPK Modeling Workflow in R: Simulation, Optimization & Visualization

October 9 @ 11:00 am - 3:00 pm
R/Pharma Conference, (Virtual) + Google Map

After a brief introduction to mrgsolve (https://mrgsolve.github.io), we will discuss concepts and applications for using the package in R to simulate from pharmacokinetic (PK) and physiologically-based PK (PBPK) models, estimate parameters given a model and data, and visualize simulation results with a Shiny app. We will establish a basic framework for running optimization in R and work hands-on examples using different optimizers, including local and global search algorithms. Building on this framework, we will also illustrate related workflows including global…

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